You can read more about research phases on the FDA’s website<\/a>.)<\/p>\nThe remaining $80 million would come through a to-be-established joint-development agreement between Apellis and SFJ Pharmaceuticals. The companies have a letter of intent to negotiate terms to support Apellis’ clinical development of APL-2 in treating two rare autoimmune blood disorders: cold agglutinin disease, or CAD, and warm antibody hemolytic anemia, or wAIHA.<\/p>\n
Apellis would get $30 million in funding after a joint-development agreement is established and as much as $50 million if Apellis achieves clinical milestones in its CAD and wAIHA research.<\/p>\n
Apellis will retain full commercial right to all of APL-2’s treatments worldwide and will maintain financial flexibility with this deal, according to the release.<\/p>\n
Apellis would pay $2.5 million back to SFJ Pharmaceutical for each final regulatory approval Apellis receives from the Food and Drug Administration and the European Medicines Agency, the FDA equivalent for the European Union. On top of that, Apellis would pay SFJ an additional $192.5\u00a0million in six annual payments after APL-2 is approved by the Food and Drug Administration to treat PNH.<\/p>\n
The annual payment amount doubles to $385\u00a0million if Apellis’ PNH treatment receives approval by both agencies.<\/p>\n
But Apellis won’t have to pay SFJ Pharmaceuticals back if PNH does not receive regulatory approval, Francois said.<\/p>\n
“[SFJ Pharmaceutical] is also placing a bet on Apellis’ capability to commercialize to a level that will allow us to pay them back in turn,” Francois said. “By any account, this is a very innovative way to finance this project.”<\/p>\n","protected":false},"excerpt":{"rendered":"
By Chris Larson \u00a0\u2013\u00a0 Reporter, Louisville Business First Feb 28, 2019 Apellis Pharmaceuticals Inc. has reached a deal with a globally oriented drug development company that could give Apellis as much as $250 million in financing through what Apellis calls “a novel, risk-sharing collaboration.” Apellis,…<\/p>\n","protected":false},"author":8,"featured_media":0,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[103],"tags":[],"class_list":["post-8529","post","type-post","status-publish","format-standard","hentry","category-news"],"yoast_head":"\n
Apellis lands as much as $250M in financing from drug development company - SFJ Pharmaceuticals<\/title>\n \n \n \n \n \n \n \n \n \n \n \n \n \n\t \n\t \n\t \n